Brian Thacher Murphy

Chemistry, drug-lead discovery, spectroscopy, aquatic microbiology

• Clark C, Costa M, Conley E, Li E, Sanchez L, Murphy BT. Using the Open-Source MALDI TOF-MS IDBac Pipeline for Analysis of Microbial Protein and Specialized Metabolite Data.. Journal of visualized experiments : JoVE. 2019;(147). doi:10.3791/59219.

• Braesel J, Clark C, Kunstman KJ, Green SJ, Maienschein-Cline M, Murphy BT, Eustáquio AS. Genome Sequence of Marine-Derived Streptomyces sp. Strain F001, a Producer of Akashin A and Diazaquinomycins.. Microbiology resource announcements. 2019;8(19). doi:10.1128/MRA.00165-19.

• Braesel J, Lee J, Arnould B, Murphy BT, Eustáquio AS. Diazaquinomycin Biosynthetic Gene Clusters from Marine and Freshwater Actinomycetes.. Journal of natural products. 2019;82(4):937-946. doi:10.1021/acs.jnatprod.8b01028.

• Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, Dorjsuren D, Eastman RT, Huang R, Iannotti MJ, Karavadhi S, Klumpp-Thomas C, Roth JS, Sakamuru S, Sun W, Titus SA, Yasgar A, Zhang YQ, Zhao J, Andrade RB, Brown MK, Burns NZ, Cha JK, Mevers EE, Clardy J, Clement JA, Crooks PA, Cuny GD, Ganor J, Moreno J, Morrill LA, Picazo E, Susick RB, Garg NK, Goess BC, Grossman RB, Hughes CC, Johnston JN, Joullie MM, Kinghorn AD, Kingston DGI , Krische MJ, Kwon O, Maimone TJ, Majumdar S, Maloney KN, Mohamed E, Murphy BT, Nagorny P, Olson DE, Overman LE, Brown LE, Snyder JK, Porco JA, Jr F, Rivas SA, Ross R, Sarpong I, Sharma JT, Shaw Z, Xu B, Shen W, Shi , Stephenson CRJ AL, Verano DS, Tan Y, Tang RE, Taylor RJ, Thomson DA, Vosburg J, Wu WM, Wuest A, Zakarian Y, Zhang T, Ren Z, Zuo J, Inglese S, Michael A, Simeonov W, Zheng P, Shinn A, Jadhav MB, Boxer MD, Hall M, Xia R, Guha JM, Rohde . Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.. ACS central science. 2018;4(12):1727-1741. doi:10.1021/acscentsci.8b00747.

• Petrovich M, Chu B, Wright D, Griffin J, Elfeki M, Murphy BT, Poretsky R, Wells G. Antibiotic resistance genes show enhanced mobilization through suspended growth and biofilm-based wastewater treatment processes.. FEMS microbiology ecology. 2018;94(11). doi:10.1093/femsec/fiy174.

• Braesel J, Crnkovic C, Kunstman KJ, Green SJ, Maienschein-Cline M, Orjala J, Murphy BT, Eustáquio AS. Complete Genome of Micromonospora sp. Strain B006 Reveals Biosynthetic Potential of a Lake Michigan Actinomycete.. Journal of natural products. 2018;81(9):2057-2068. doi:10.1021/acs.jnatprod.8b00394.

• Lee J, Dean MJ, Austin J, Burdette JE, Murphy BT. Irilone from Red Clover ( Trifolium pratense) Potentiates Progesterone Signaling.. Journal of natural products. 2018;81(9):1962-1967. doi:10.1021/acs.jnatprod.8b00131.

• Elfeki M, Alanjary M, Green SJ, Ziemert N, Murphy BT. Assessing the Efficiency of Cultivation Techniques To Recover Natural Product Biosynthetic Gene Populations from Sediment.. ACS chemical biology. 2018;13(8):2074-2081. doi:10.1021/acschembio.8b00254.

• Clark C, Costa M, Sanchez L, Murphy BT. Coupling MALDI-TOF mass spectrometry protein and specialized metabolite analyses to rapidly discriminate bacterial function.. Proceedings of the National Academy of Sciences of the United States of America. 2018;115(19):4981-4986. doi:10.1073/pnas.1801247115.

• Petrovich M, Chu B, Wright D, Griffin J, Elfeki M, Murphy BT, Poretsky R, Wells G. Antibiotic resistance genes show enhanced mobilization through suspended growth and biofilm-based wastewater treatment processes.. FEMS microbiology ecology. 2018;94(5). doi:10.1093/femsec/fiy041.