Photo of Dejan Nikolic

Dejan Nikolic


INST AFFL, Institute for Tuberculosis Research
Research Associate Professor, Pharmaceutical Sciences

Contact

Building & Room:

435 PHARM, MC 781

Address:

833 S. Wood Street, Chicago, IL, 60612

Office Phone:

(312) 413-5867

Email:

dnikol1@uic.edu

Selected Publications

  • Huang L, Nikolic DS, van Breemen RB. “Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry”. Analytical and Bioanalytical Chemistry. 2017;409(30):6937-6948. doi:10.1007/s00216-017-0642-x.

  • Li G, Simmler C, Chen L, Nikolic DS, Chen SN, Pauli GF, van Breemen RB. “Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents”. European Journal of Pharmaceutical Sciences. 2017;109:182-190. doi:10.1016/j.ejps.2017.07.034.

  • Keiler AM, Macejova D, Dietz BM, Bolton JL, Pauli GF, Chen SN, van Breemen RB, Nikolic DS, Goerl F, Muders MH, Zierau O, Vollmer G. “Evaluation of estrogenic potency of a standardized hops extract on mammary gland biology and on MNU-induced mammary tumor growth in rats”. Journal of Steroid Biochemistry and Molecular Biology. 2017;174:234-241. doi:10.1016/j.jsbmb.2017.09.020.

  • Keiler AM, Helle J, Bader MI, Ehrhardt T, Nestler K, Kretzschmar G, Bernhardt R, Vollmer G, Nikolic DS, Bolton JL, Pauli GF, Chen SN, Dietz BM, van Breemen RB, Zierau O. “A standardized Humulus lupulus (L.) ethanol extract partially prevents ovariectomy-induced bone loss in the rat without induction of adverse effects in the uterus”. Phytomedicine. 2017;34:50-58. doi:10.1016/j.phymed.2017.08.001.

  • Nikolic DS, Macias C, Lankin DC, van Breemen RB. “Collision-induced dissociation of phenethylamides: role of ion-neutral complexes”. Rapid Communications in Mass Spectrometry. 2017;31(17):1385-1395. doi:10.1002/rcm.7915.

  • Nikolic DS. (2017). “CASMI 2016: A manual approach for dereplication of natural products using tandem mass spectrometry”. Phytochemistry Letters. Vol. 21. Page(s) 292-296. https://api.elsevier.com/content/abstract/scopus_id/85011343089

  • Simmler C, Lankin DC, Nikolic DS, van Breemen RB, Pauli GF. “Isolation and structural characterization of dihydrobenzofuran congeners of licochalcone A”. Fitoterapia. 2017;121:6-15. doi:10.1016/j.fitote.2017.06.017.

  • Dietz BM, Chen SN, Alvarenga RF, Dong H, Nikolic DS, Biendl M, van Breemen RB, Bolton JL, Pauli GF. “DESIGNER Extracts as Tools to Balance Estrogenic and Chemopreventive Activities of Botanicals for Women’s Health”. Journal of Natural Products. 2017;80(8):2284-2294. doi:10.1021/acs.jnatprod.7b00284.

  • Li G, Nikolic DS, van Breemen RB. “Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS”. Journal of Agricultural and Food Chemistry. 2016;64(42):8062-8070. doi:10.1021/acs.jafc.6b02954.

  • Imai A, Lankin DC, Nikolic DS, Ahn S, van Breemen RB, Farnsworth NR, McAlpine JB, Chen SN, Pauli GF. “Cycloartane Triterpenes from the Aerial Parts of Actaea racemosa”. Journal of Natural Products. 2016;79(3):541-554. doi:10.1021/acs.jnatprod.5b00927.

  • Hajirahimkhan A, Simmler C, Dong H, Lantvit DD, Li G, Chen S, Nikolic DS, Pauli GF, van Breemen RB, Dietz BM, Bolton JL. Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women’s Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A.. Chemical research in toxicology. 2015;28(11):2130-41. doi:10.1021/acs.chemrestox.5b00310.

  • Hajirahimkhan A, Simmler C, Dong H, Lantvit DD, Li G, Chen SS, Nikolic DF, Pauli GB, van Breemen RM, Dietz BL, Bolton J. Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women’s Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A.. Chemical research in toxicology. 2015;28(11):2130-41. doi:10.1021/acs.chemrestox.5b00310.

  • Ramos Alvarenga RF, Friesen JB, Nikolic DS, Simmler C, Napolitano JG, van Breemen RB, Lankin DC, McAlpine JB, Pauli GF, Chen S. K-targeted metabolomic analysis extends chemical subtraction to DESIGNER extracts: selective depletion of extracts of hops (Humulus lupulus).. Journal of natural products. 2014;77(12):2595-604. doi:10.1021/np500376g.

  • van Breemen RB, Yuan YP, Banuvar SF, Shulman L, Qiu XM, Alvarenga RL, Chen SF, Dietz BC, Bolton JS, Pauli G, Krause E, Viana M, Nikolic D. Pharmacokinetics of prenylated hop phenols in women following oral administration of a standardized extract of hops.. Molecular nutrition & food research. 2014;58(10):1962-9. doi:10.1002/mnfr.201400245.

  • Simmler C, Nikolic DS, Lankin DC, Yu Y, Friesen JB, van Breemen RB, Lecomte AF, Le Quémener C, Audo G, Pauli G. Orthogonal Analysis Underscores the Relevance of Primary and Secondary Metabolites in Licorice.. Journal of natural products. 2014;77(8):1806-16. doi:10.1021/np5001945.

  • Simmler C, Jones TR, Anderson JS, Nikolic DB, van Breemen RD, Soejarto D, Chen SF, Pauli G. Species-specific Standardisation of Licorice by Metabolomic Profiling of Flavanones and Chalcones.. Phytochemical analysis : PCA. 2014;25(4):378-88.

  • Krause EC, Yuan Y, Hajirahimkhan A, Dong HM, Dietz BS, Nikolic DF, Pauli GL, Bolton JB, van Breemen R. Biological and chemical standardization of a hop (Humulus lupulus) botanical dietary supplement.. Biomedical chromatography : BMC. 2014;28(6):729-34. doi:10.1002/bmc.3177.

  • Hajirahimkhan A, Simmler C, Yuan YR, Anderson J, Chen SS, Nikolic DM, Dietz BF, Pauli GB, van Breemen RL, Bolton J. Evaluation of estrogenic activity of licorice species in comparison with hops used in botanicals for menopausal symptoms.. PloS one. 2013;8(7):e67947. doi:10.1371/journal.pone.0067947.

  • Dietz BM, Hagos GK, Eskra JN, Wijewickrama GT, Anderson JR, Nikolic DS, Guo JJ, Wright B, Chen SF, Pauli GB, van Breemen RL, Bolton J. Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo.. Molecular nutrition & food research. 2013;57(6):1055-66. doi:10.1002/mnfr.201200534.

  • Dong SH, Nikolic DS, Simmler C, Qiu FB, van Breemen RD, Soejarto DF, Pauli G, Chen S. Diarylheptanoids from Dioscorea villosa (Wild Yam).. Journal of natural products. 2012;75(12):2168-77. doi:10.1021/np300603z.

  • Yuan YS, Qiu XH, Nikolic DB, Dahl J, van Breemen R. Method development and validation for ultra-high-pressure LC/MS/MS determination of hop prenylflavonoids in human serum.. Journal of AOAC International. 2012;95(6):1744-9.

  • Hu CS, Nikolic DL, Eggler AD, Mesecar AB, van Breemen R. Screening for natural chemoprevention agents that modify human Keap1.. Analytical biochemistry. 2012;421(1):108-14. doi:10.1016/j.ab.2011.10.028.

  • Chen S, Webster DS, Nikolic DB, van Breemen R, Wang ZH, Fong HR, Farnsworth NF, Pauli G. Phytoconstituents from Vitex agnus-castus fruits.. Fitoterapia. 2011;82(4):528-33. doi:10.1016/j.fitote.2010.12.003.

  • Cao HS, Yu RB, Tao Y, Nikolic D, van Breemen R. Measurement of cyclooxygenase inhibition using liquid chromatography-tandem mass spectrometry.. Journal of pharmaceutical and biomedical analysis. 2011;54(1):230-5. doi:10.1016/j.jpba.2010.08.001.

  • Bolca SS, Li JB, Nikolic D, Roche N, Blondeel P, Possemiers S, De Keukeleire D, Bracke M, Heyerick A, van Breemen R, Depypere H. Disposition of hop prenylflavonoids in human breast tissue.. Molecular nutrition & food research. 2010;54 Suppl 2:S284-94. doi:10.1002/mnfr.200900519.

  • Inui TS, Wang YC, Nikolic DG, Smith DF, Franzblau S, Pauli G. Sesquiterpenes from Oplopanax horridus.. Journal of natural products. 2010;73(4):563-7. doi:10.1021/np900674d.

  • van Breemen RB, Liang WP, Banuvar S, Shulman LS, Pang YM, Tao Y, Nikolic DL, Krock KF, Chen SE, Hedayat SC, Bolton JE, Pauli GR, Piersen C, Krause E, Geller S, Farnsworth N. Pharmacokinetics of 23-epi-26-deoxyactein in women after oral administration of a standardized extract of black cohosh.. Clinical pharmacology and therapeutics. 2010;87(2):219-25. doi:10.1038/clpt.2009.251.

  • Geller SE, Shulman LP, van Breemen RB, Banuvar SS, Zhou YC, Epstein GE, Hedayat SL, Nikolic DF, Krause ER, Piersen C, Bolton J, Pauli G, Farnsworth N. Safety and efficacy of black cohosh and red clover for the management of vasomotor symptoms: a randomized controlled trial.. Menopause (New York, N.Y.). 2009;16(6):1156-66. doi:10.1097/gme.0b013e3181ace49b.

  • Gödecke TC, Lankin DS, Nikolic D, Chen SB, van Breemen RR, Farnsworth NF, Pauli G. Guanidine alkaloids and Pictet-Spengler adducts from black cohosh (Cimicifuga racemosa).. Journal of natural products. 2009;72(3):433-7. doi:10.1021/np8006952.

  • Gödecke TS, Nikolic DC, Lankin D, Chen SL, Powell SM, Dietz BL, Bolton JB, van Breemen RR, Farnsworth NF, Pauli G. Phytochemistry of cimicifugic acids and associated bases in Cimicifuga racemosa root extracts.. Phytochemical analysis : PCA. 2009;20(2):120-33. doi:10.1002/pca.1106.

  • Powell SL, Gödecke TS, Nikolic D, Chen SM, Ahn SR, Dietz BB, Farnsworth NC, van Breemen RF, Lankin DL, Pauli G, Bolton J. In vitro serotonergic activity of black cohosh and identification of N(omega)-methylserotonin as a potential active constituent.. Journal of agricultural and food chemistry. 2008;56(24):11718-26. doi:10.1021/jf803298z.

  • Chen S, Turner AU, Jaki BS, Nikolic DB, van Breemen RF, Pauli G. An experimental implementation of chemical subtraction.. Journal of pharmaceutical and biomedical analysis. 2008;46(4):692-8. doi:10.1016/j.jpba.2007.12.014.

  • Guo JS, Liu DM, Nikolic DB, Zhu D, Pezzuto J, van Breemen R. In vitro metabolism of isoliquiritigenin by human liver microsomes.. Drug metabolism and disposition: the biological fate of chemicals. 2008;36(2):461-8. doi:10.1124/dmd.107.018721.

  • Pang Y, Nikolic DS, Zhu DR, Chadwick LF, Pauli GR, Farnsworth NB, van Breemen R. Binding of the hop (Humulus lupulus L.) chalcone xanthohumol to cytosolic proteins in Caco-2 intestinal epithelial cells.. Molecular nutrition & food research. 2007;51(7):872-9. doi:10.1002/mnfr.200600252.

  • Chen S, Lankin DC, Nikolic DS, Lu ZZ, Ramirez BB, van Breemen RH, Fong HR, Farnsworth NF, Pauli G. Chlorination diversifies Cimicifuga racemosa triterpene glycosides.. Journal of natural products. 2007;70(6):1016-23. doi:10.1021/np0700319.

  • Wang Z, Yuan HS, Nikolic DB, van Breemen RB, Silverman R. (+/-)-(1S,2R,5S)-5-Amino-2-fluorocyclohex-3-enecarboxylic acid. A potent GABA aminotransferase inactivator that irreversibly inhibits via an elimination-aromatization pathway.. Biochemistry. 2006;45(48):14513-22. doi:10.1021/bi061592m.

  • Deng S, Chen S, Lu JS, Wang ZB, Nikolic DD, van Breemen RH, Santarsiero BR, Mesecar AF, Fong H, Farnsworth N, Pauli G. GABAergic phthalide dimers from Angelica sinensis (Oliv.) Diels.. Phytochemical analysis : PCA. 2006;17(6):398-405.

  • Deng S, Chen S, Lu JS, Wang ZB, Nikolic DD, van Breemen RH, Santarsiero BR, Mesecar AF, Fong H, Farnsworth N, Pauli G. GABAergic phthalide dimers from Angelica sinensis (Oliv.) Diels.. Phytochemical analysis : PCA. 2006;17(6):398-405.

  • Guo JS, Nikolic DR, Chadwick LF, Pauli GB, van Breemen R. Identification of human hepatic cytochrome P450 enzymes involved in the metabolism of 8-prenylnaringenin and isoxanthohumol from hops (Humulus lupulus L.).. Drug metabolism and disposition: the biological fate of chemicals. 2006;34(7):1152-9. doi:10.1124/dmd.105.008250.

  • Nikolic DS, Li YR, Chadwick LB, van Breemen R. In vitro studies of intestinal permeability and hepatic and intestinal metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus L.).. Pharmaceutical research. 2006;23(5):864-72. doi:10.1007/s11095-006-9902-8.

  • Deng S, Chen SS, Yao PB, Nikolic DL, van Breemen RH, Bolton JR, Fong HF, Farnsworth N, Pauli G. Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis.. Journal of natural products. 2006;69(4):536-41. doi:10.1021/np050301s.

  • Booth NL, Overk CR, Yao PE, Burdette JS, Nikolic D, Chen SL, Bolton JB, van Breemen RF, Pauli GR, Farnsworth N. The chemical and biologic profile of a red clover (Trifolium pratense L.) phase II clinical extract.. Journal of alternative and complementary medicine (New York, N.Y.). 2006;12(2):133-9. doi:10.1089/acm.2006.12.133.

  • Overk CR, Yao PR, Chadwick LS, Nikolic DK, Ajayi OA, Cuendet MS, Deng YF, Hedayat AR, Pauli GB, Farnsworth NL, van Breemen R, Bolton J. Comparison of the in vitro estrogenic activities of compounds from hops (Humulus lupulus) and red clover (Trifolium pratense).. Journal of agricultural and food chemistry. 2005;53(16):6246-53. doi:10.1021/jf050448p.

  • Nikolic DS, Lankin DC, Chen S, Jaki BU, Krunic A, van Breemen RB, Fong HH, Farnsworth NR, Pauli GF. Cimipronidine, a cyclic guanidine alkaloid from Cimicifuga racemosa.. Journal of natural products. 2005;68(8):1266-70. doi:10.1021/np050066d.

  • Nikolic DS, Li YR, Chadwick LF, Pauli GB, van Breemen R. Metabolism of xanthohumol and isoxanthohumol, prenylated flavonoids from hops (Humulus lupulus L.), by human liver microsomes.. Journal of mass spectrometry : JMS. 2005;40(3):289-99. doi:10.1002/jms.753.

  • Zhu YS, Nikolic DB, van Breemen RB, Silverman R. Mechanism of inactivation of inducible nitric oxide synthase by amidines. Irreversible enzyme inactivation without inactivator modification.. Journal of the American Chemical Society. 2005;127(3):858-68. doi:10.1021/ja0445645.

  • Booth NL, Nikolic DS, van Breemen RB, Geller SE, Banuvar SP, Shulman LR, Farnsworth N. Confusion regarding anticoagulant coumarins in dietary supplements.. Clinical pharmacology and therapeutics. 2004;76(6):511-6. doi:10.1016/j.clpt.2004.08.023.

  • Chadwick LR, Nikolic DS, Burdette JE, Overk CR, Bolton JL, van Breemen RB, Fröhlich RH, Fong HR, Farnsworth NF, Pauli G. Estrogens and congeners from spent hops (Humulus lupulus).. Journal of natural products. 2004;67(12):2024-32. doi:10.1021/np049783i.

  • Li YS, Grubjesic SW, Nikolic DM, Zhu DM, Kosmeder JB, Moriarty R, Pezzuto J, van Breemen R. In vitro assessment of intestinal permeability and hepatic metabolism of 4′-bromoflavone, a promising cancer chemopreventive agent.. Xenobiotica; the fate of foreign compounds in biological systems. 2004;34(6):535-47. doi:10.1080/00498250410001713159.

  • Li YS, Yao JD, Chang MD, Nikolic DB, Yu LL, Yager J, Mesecar A, van Breemen R, Bolton J. Equine catechol estrogen 4-hydroxyequilenin is a more potent inhibitor of the variant form of catechol-O-methyltransferase.. Chemical research in toxicology. 2004;17(4):512-20. doi:10.1021/tx0342464.

  • Nikolic DS, van Breemen RB. New metabolic pathways for flavanones catalyzed by rat liver microsomes.. Drug metabolism and disposition: the biological fate of chemicals. 2004;32(4):387-97. doi:10.1124/dmd.32.4.387.

  • Nikolic DS, Li YR, Chadwick LB, Grubjesic S, Schwab P, Metz P, van Breemen R. Metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus), by human liver microsomes.. Drug metabolism and disposition: the biological fate of chemicals. 2004;32(2):272-9. doi:10.1124/dmd.32.2.272.

  • Liu JE, Burdette JM, Sun YS, Deng SB, Schlecht SB, Zheng WH, Nikolic DM, Mahady GL, van Breemen RR, Fong H, Pezzuto J, Bolton J, Farnsworth N. Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry).. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2004;11(1):18-23. doi:10.1078/0944-7113-00331.

  • Lu XS, Nikolic DJ, Mitchell DB, van Breemen RA, Mersfelder JB, Hille R, Silverman R. A mechanism for substrate-Induced formation of 6-hydroxyflavin mononucleotide catalyzed by C30A trimethylamine dehydrogenase.. Bioorganic & medicinal chemistry letters. 2003;13(22):4129-32.

  • Kouloumbos VN, Tsipi DF, Hiskia AE, Nikolic DS, van Breemen RB. Identification of photocatalytic degradation products of diazinon in TiO2 aqueous suspensions using GC/MS/MS and LC/MS with quadrupole time-of-flight mass spectrometry.. Journal of the American Society for Mass Spectrometry. 2003;14(8):803-17. doi:10.1016/S1044-0305(03)00333-7.

  • Su BN, Park EJ, Nikolic DS, Schunke Vigo JG, Graham JB, Cabieses FH, van Breemen RR, Fong HM, Farnsworth N, Pezzuto J. Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora.. Journal of natural products. 2003;66(8):1089-93. doi:10.1021/np030081n.

  • Su BN, Park EJ, Nikolic DS, Santarsiero BD, Mesecar AD, Vigo JS, Graham JG, Cabieses FB, van Breemen RH, Fong HR, Farnsworth NM, Pezzuto J. Activity-guided isolation of novel norwithanolides from depreasubtriflora with potential cancer chemopreventive activity.. The Journal of organic chemistry. 2003;68(6):2350-61. doi:10.1021/jo020542u.

  • Su BN, Park EJ, Nikolic DS, Santarsiero BD, Mesecar AD, Vigo JS, Graham JG, Cabieses FB, van Breemen RH, Fong HR, Farnsworth NM, Pezzuto JD, Kinghorn A. Activity-guided isolation of novel norwithanolides from depreasubtriflora with potential cancer chemopreventive activity.. The Journal of organic chemistry. 2003;68(6):2350-61. doi:10.1021/jo020542u.

  • Yang YS, Nikolic DM, Swanson SB, van Breemen R. Quantitative determination of N7-methyldeoxyguanosine and O6-methyldeoxyguanosine in DNA by LC-UV-MS-MS.. Analytical chemistry. 2002;74(20):5376-82.

  • Johnson BM, Nikolic DS, van Breemen RB. Applications of pulsed ultrafiltration-mass spectrometry.. Mass spectrometry reviews. 2002;21(2):76-86. doi:10.1002/mas.10020.

  • Mitchell DJ, Nikolic DS, Jang MH, van Breemen RB, Hille RB, Silverman R. Inactivation of C30A trimethylamine dehydrogenase by N-cyclopropyl-alpha-methylbenzylamine, 1-phenylcyclopropylamine, and phenylhydrazine.. Biochemistry. 2001;40(29):8523-30.

  • Mitchell DJ, Nikolic DS, van Breemen RB, Silverman RB. Inactivation of monoamine oxidase B by 1-phenylcyclopropylamine: mass spectral evidence for the flavin adduct.. Bioorganic & medicinal chemistry letters. 2001;11(13):1757-60.

  • Mitchell DJ, Nikolic DS, Rivera EO, Sablin SA, Choi SB, van Breemen RP, Singer TB, Silverman R. Spectrometric evidence for the flavin-1-phenylcyclopropylamine inactivator adduct with monoamine oxidase N.. Biochemistry. 2001;40(18):5447-56.

  • Nikolic DS, van Breemen RB. DNA oxidation induced by cyclooxygenase-2.. Chemical research in toxicology. 2001;14(4):351-4.

  • Nikolic DS, Habibi-Goudarzi SG, Corley DM, Gafner SB, Pezzuto J, van Breemen R. Evaluation of cyclooxygenase-2 inhibitors using pulsed ultrafiltration mass spectrometry.. Analytical chemistry. 2000;72(16):3853-9.

  • Gu CS, Nikolic DB, Lai J, Xu X, van Breemen R. Assays of ligand-human serum albumin binding using pulsed ultrafiltration and liquid chromatography-mass spectrometry.. Combinatorial chemistry & high throughput screening. 1999;2(6):353-9.

  • Korecka MS, Nikolic DB, van Breemen RM, Shaw L. The apparent inhibition of inosine monophosphate dehydrogenase by mycophenolic acid glucuronide is attributable to the presence of trace quantities of mycophenolic acid.. Clinical chemistry. 1999;45(7):1047-50.

  • Nikolic DS, Fan PW, Bolton JL, van Breemen RB. Screening for xenobiotic electrophilic metabolites using pulsed ultrafiltration-mass spectrometry.. Combinatorial chemistry & high throughput screening. 1999;2(3):165-75.

  • Chen YS, Shen LB, Zhang FS, Lau SL, van Breemen R, Nikolic D, Bolton J. The equine estrogen metabolite 4-hydroxyequilenin causes DNA single-strand breaks and oxidation of DNA bases in vitro.. Chemical research in toxicology. 1998;11(9):1105-11. doi:10.1021/tx980083l.

  • Nikolic DS, van Breemen RB. Screening for inhibitors of dihydrofolate reductase using pulsed ultrafiltration mass spectrometry.. Combinatorial chemistry & high throughput screening. 1998;1(1):47-55.

  • Shen LB, Qiu SS, Chen YL, Zhang F, van Breemen R, Nikolic D, Bolton J. Alkylation of 2′-deoxynucleosides and DNA by the Premarin metabolite 4-hydroxyequilenin semiquinone radical.. Chemical research in toxicology. 1998;11(2):94-101. doi:10.1021/tx970181r.

  • van Breemen RB, Nikolic DS, Bolton JL. Metabolic screening using on-line ultrafiltration mass spectrometry.. Drug metabolism and disposition: the biological fate of chemicals. 1998;26(2):85-90.

  • van Breemen RB, Nikolic DS, Xu XE, Xiong YB, van Lieshout M, West C, Schilling A. Development of a method for quantitation of retinol and retinyl palmitate in human serum using high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry.. Journal of chromatography. A. 1998;794(1-2):245-51.

  • Zhao YZ, van Breemen RB, Nikolic DS, Huang CR, Woodbury CP, Schilling A. Screening solution-phase combinatorial libraries using pulsed ultrafiltration/electrospray mass spectrometry.. Journal of medicinal chemistry. 1997;40(25):4006-12. doi:10.1021/jm960729b.

  • van Breemen RB, Huang CR, Nikolic DS, Woodbury CP, Zhao YZ. Pulsed ultrafiltration mass spectrometry: a new method for screening combinatorial libraries.. Analytical chemistry. 1997;69(11):2159-64.