Photo of Cho, Sang Hyun

Sang Hyun Cho

Research Professor of Medicinal Chemistry, Pharmaceutical Sciences Associate Director, Institute for Tuberculosis Research

Contact

Building & Room:

412C PHARM, MC 964

Address:

833 S. Wood Street, Chicago, IL, 60612

Office Phone:

(312) 355-4521

Office Phone TTY:

(312) 996-2693

Email:

jkcno1@uic.edu

Selected Publications

  • Tiwari RA, Miller P, Cho SG, Franzblau SJ, Miller M. Syntheses and Antituberculosis Activity of 1,3-Benzothiazinone Sulfoxide and Sulfone Derived from BTZ043.. ACS medicinal chemistry letters. 2015;6(2):128-33. doi:10.1021/ml5003458.

 

  • Gao WY, Kim JR, Anderson J, Akopian TY, Hong SW, Jin YA, Kandror OY, Kim JG, Lee IH, Lee SM, Mulugeta SL, Sunoqrot SF, Wang YW, Yang SG, Yoon T, Goldberg A, Pauli G, Suh J, Franzblau S, Cho S. The cyclic peptide ecumicin targeting ClpC1 is active against Mycobacterium tuberculosis in vivo.. Antimicrobial agents and chemotherapy. 2015;59(2):880-9. doi:10.1128/AAC.04054-14.

 

  • Upton AM, Cho S, Yang TJ, Kim Y, Wang YG, Lu Y, Wang B, Xu J, Mdluli K, Ma Z, Franzblau S. In vitro and in vivo activities of the nitroimidazole TBA-354 against Mycobacterium tuberculosis.. Antimicrobial agents and chemotherapy. 2015;59(1):136-44. doi:10.1128/AAC.03823-14.

 

  • Gao WY, Kim J, Chen S, Cho SU, Choi JY, Jaki BC, Jin YE, Lankin DY, Lee JG, Lee SG, Napolitano JW, Franzblau SF, Suh J, Pauli G. Discovery and characterization of the tuberculosis drug lead ecumicin.. Organic letters. 2014;16(23):6044-7. doi:10.1021/ol5026603.

 

  • Moraski GC, Oliver AG, Markley LD, Cho S, Franzblau SG, Miller MJ. Scaffold-switching: an exploration of 5,6-fused bicyclic heteroaromatics systems to afford antituberculosis activity akin to the imidazo[1,2-a]pyridine-3-carboxylates.. Bioorganic & medicinal chemistry letters. 2014;24(15):3493-8. doi:10.1016/j.bmcl.2014.05.062.

 

  • Tiwari R, Möllmann UG, Cho SA, Franzblau SJ, Miller P, Miller M. Design and Syntheses of Anti-Tuberculosis Agents Inspired by BTZ043 Using a Scaffold Simplification Strategy.. ACS medicinal chemistry letters. 2014;5(5):587-91. doi:10.1021/ml500039g.

 

  • Pieroni M, Wan B, Cho SG, Franzblau S, Costantino G. Design, synthesis and investigation on the structure-activity relationships of N-substituted 2-aminothiazole derivatives as antitubercular agents.. European journal of medicinal chemistry. 2014;72:26-34. doi:10.1016/j.ejmech.2013.11.007.

 

  • Cai GG, Napolitano JU, Wang YW, Jaki BH, Suh JA, Yang SG, Lee IF, Franzblau S, Pauli G, Cho S. Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain.. Journal of natural products. 2013;76(11):2009-18. doi:10.1021/np400145u.

 

  • Hwang CH, Jaki BU, Klein L, Lankin DC, Napolitano JG, Fryling NA, Franzblau SG, Cho S, Stamets PE, Wang YF, Pauli G. Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis.. Journal of natural products. 2013;76(10):1916-22. doi:10.1021/np400497f.

 

  • Grant SS, Kawate TP, Nag PR, Silvis MA, Stanley S, Kazyanskaya EG, Nietupski RT, Golas A, Cho S, Franzblau S, Hung D. Identification of novel inhibitors of nonreplicating Mycobacterium tuberculosis using a carbon starvation model.. ACS chemical biology. 2013;8(10):2224-34. doi:10.1021/cb4004817.

 

Education

  • PhD, Mycobacteriology, Konkuk Univ, Seoul, Korea

    • Professional Memberships

    • American Society of Microbiology